RGX-104 free Acid

CAS No. 610318-54-2

RGX-104 free Acid( —— )

Catalog No. M21011 CAS No. 610318-54-2

RGX-104 free Acid is an agonist of potent liver-X nuclear hormone receptor (LXR)?.

RGX-104 free Acid is an agonist of potent liver-X nuclear hormone receptor (LXR)?.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 80 Get Quote
5MG 125 Get Quote
10MG 200 Get Quote
25MG 402 Get Quote
50MG 593 Get Quote
100MG 845 Get Quote
200MG Get Quote Get Quote
500MG Get Quote Get Quote
1G Get Quote Get Quote

Biological Information

  • Product Name
    RGX-104 free Acid
  • Note
    Research use only, not for human use.
  • Brief Description
    RGX-104 free Acid is an agonist of potent liver-X nuclear hormone receptor (LXR)?.
  • Description
    RGX-104 free Acid is an agonist of potent liver-X nuclear hormone receptor (LXR)?.
  • In Vitro
    ——
  • In Vivo
    Animal Model:NOD SCID or RAG mice injected with 1×106 SKOV3 ovarian cancer cells.Dosage:100 mg/kg.Administration:Oral administration daily for about 60 days.Result:Robustly suppressed tumor growth and progression.
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    LXRβ
  • Research Area
    Cancer
  • Indication
    Lymphoma; Solid tumours

Chemical Information

  • CAS Number
    610318-54-2
  • Formula Weight
    596.08
  • Molecular Formula
    C34H33ClF3NO3
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:130 mg/mL (218.09 mM)
  • SMILES
    C[C@H](CCOc1cccc(CC(=O)O)c1)N(Cc1cccc(C(F)(F)F)c1Cl)CC(c1ccccc1)c1ccccc1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Tavazoie M F Pollack I Tanqueco R et al. LXR/ApoE Activation Restricts Innate Immune Suppression in Cancer[J]. Cell 2018:S0092867417315064.
molnova catalog
related products
  • Cryptochlorogenic ac...

    Cryptochlorogenic acid has antioxidant activity.

  • MOZ-IN-2

    MOZ-IN-2 is an protein MOZ inhibitor(IC50 of 125 μM).

  • 26-Dimethylaniline

    26-Xylidine is an aniline derivative with the chemical formula (CH3)2C6H3NH2. It is an isomer of 24-xylidine and 34-xylidine. It is a colourless liquid although commercial samples can appear to be yellow or even red.